The Ministry of Interior (MOI) said the blast happened close to the Sayeed-ul-Shuhada School in the Dasht-e-Barchi area on Saturday afternoon.
MOI spokesperson Tariq Arian said the number of casualties could increase.
Officials have not revealed the cause of the explosion, or if there was a target. There has been no claim of responsibility yet.
According to Afghanistan’s Tolo News, the incident happened when students were leaving the school. “A car bomb blast happened first, and then two more explosions occurred near the girls school in Kabul,” said Ibrahim, a schoolteacher, according to Tolo. He added that the majority of victims are girls, Tolo reports.